Carlton forward Levi Casboult and speedy recruit Jason Tutt have boarded the plane to Perth and appear likely to come into the side to face West Coast at Domain Stadium on Friday night.
Strong-marking big man Casboult was left out of the Blues' 27-point round-one loss to Richmond due to a lack of form.
But the 199cm big man, who booted 15 goals in 19 games last season, looks set to take the place of Kristian Jaksch (broken ribs) and could cause headaches for the Eagles' depleted defence.
"We're not sure what the Eagles' team is going to be so Levi has been pretty good in the reserves this year, as well as 'Tutty' with that forward pressure," utility Andrejs Everitt said on Thursday at Melbourne Airport.
"Hopefully our talls can take a few good grabs like they have in the pre-season and kick a few more goals."
West Coast will be without key backmen Eric Mackenzie and Mitch Brown for the rest of the season, with the pair recently suffering season-ending anterior cruciate ligament injuries.
However, 196cm Will Schofield (ankle) is set to return to a key defensive post for the Eagles alongside impressive youngster Jeremy McGovern.
Casboult booted one goal and had a strong physical presence for the Northern Blues in a VFL practice match on Good Friday, while Tutt collected 21 disposals and kicked a clever goal playing up forward and on a wing.
The pacy 23-year-old could replace injured star Dale Thomas (shoulder) for his first Carlton appearance after he walked out on the Western Bulldogs at the end of last year following 26 games and 22 goals in four seasons.
"[Tutt] and David Ellard were really good at that last year, and that's why we got 'Tutty' over from the Bulldogs, because he's a small forward with a lot of speed," Everitt said.
"They're hard to come by and if he can put on that forward pressure it's going to keep the position pretty open in terms of competitiveness coming through the twos."
Everitt also said maintaining pressure had been something the Blues had worked on this week in the wake of the loss to the Tigers.
"It was a little bit disappointing, the last three quarters of the game, but we started pretty well," he said.
"I think what was evident was our pressure early on.
"We worked on a few things [this week] but if we bring the pressure and the contested ball side of things it's going to hold us in good stead to put in a better four-quarter effort.
"Last week's game between the Bulldogs and West Coast was a high pressure game so we need to bring that first quarter effort again this week and hopefully we'll be right."
Some Blues players, including star midfielders Chris Judd and Marc Murphy, travelled to Perth on Wednesday to have an extra day on the ground after the long flight.
The Blues have taken a squad of 25 that includes last week's emergency David Ellard and newly promoted rookie Ciaran Byrne.
Byrne has been elevated from the rookie list in place of Cameron Giles, who is out indefinitely with a foot injury.
They are scheduled to train in Perth on Thursday afternoon.