Tom Bell and Levi Casboult, will make their senior debut after being elevated off the rookie list for Jeremy Laidler and Shaun Hampson who have each been placed on the long term injury list.
Also coming into the team are Paul Bower, Jordan Russell and Bret Thornton, who have each won a senior recall.
Out of the team is the captain Chris Judd, who now commences his four-match suspension, with Lachie Henderson, Matthew Kreuzer, Kane Lucas and Andrew Walker all unavailable through injury.
Carlton's Round 17 line-up:
B: P.Bower M.Jamison A.Joseph
HB: A.McInnes N.Duigan C.Yarran
C: B.Gibbs M.Robinson H.Scotland
HF: J.Garlett M.Watson E.Betts
F: D.Armfield B.Thornton A.Collins
Foll: L.Casboult M.Murphy A.Carrazzo
Int: T.Bell, E.Curnow, B.McLean & J.Russell
Emg: F.Dale, D.Ellard & S.White
IN: B.Thornton, J.Russell, P.Bower, L.Casboult & T.Bell
OUT: C.Judd (Suspension), A.Walker (Calf), M.Kreuzer (Hip), L.Henderson (Groin) & K.Lucas (Hamstring)
New: L.Casboult (Beaconsfield/Dandenong U18) & T.Bell (Morningside QLD)
