Jacob Weitering will make his return from a shoulder injury after being named to face North Melbourne at Etihad Stadium on Saturday night.
Daniel Gorringe will come into the Blues' side to line up for his first game of the season, while Simon White has also been named.
Matthew Kreuzer (knee), Levi Casboult (leg) and Michael Jamison (illness) will all miss.
Meanwhile, Cameron Wood has been elevated from the rookie list as the replacement for Harry McKay, who was previously placed on the club’s long-term injury list.
Meanwhile, North Melbourne has also made three changes, bringing in Michael Firrito, Farren Ray and Trent Dumont at the expense of Majak Daw (omitted), Ben Jacobs (foot) and Mason Wood (concussion).
Carlton's team to take on North Melbourne:
Backs | 38. Ciaran Byrne | 43. Simon White | 23. Jacob Weitering |
Half-backs | 15. Sam Docherty | 20. Lachie Plowman | 42. Zach Tuohy |
Centreline | 13. Jed Lamb | 9. Patrick Cripps | 27. Dennis Armfield |
Half-forwards | 39. Dale Thomas | 14. Liam Jones | 46. Matthew Wright |
Forwards | 33. Andrejs Everitt | 17. Sam Rowe | 35. Ed Curnow |
Followers | 37. Daniel Gorringe | 4. Bryce Gibbs | 3. Marc Murphy (C) |
Interchange | 6. Kade Simpson | 11. Sam Kerridge | 1. Andrew Walker |
19. Liam Sumner | |||
Emergencies | 32. Nick Graham | 12. Blaine Boekhorst | 36. Cameron Wood |
In: White, Gorringe, Weitering
Out: Michael Jamison (illness), Matthew Kreuzer (knee), Levi Casboult (leg)
New: Gorringe (Gold Coast Suns)