CHANGE breeds opportunity. 

Luke Power's side will head to Arden Street today looking for their first win of the VFL season with three players making their Carlton Reserves debuts.

As is the nature of VFL team selection, the Blues have named five changes for today's clash with North Melbourne.

Blake Kuipers, Jack Lefroy and Aidan Mills will all play their first game for the VFL Blues, joining VFL co-vice captain Lachie Swaney and defender Michael Lewis as the inclusions.

They come into the team in place of Josh Honey (AFL selection), Jack Carroll and Alex Cincotta (AFL emergencies), David Cuningham and Tyreece Leiu (injured).

Cuningham has been withdrawn from the VFL this week due to calf tightness, with the aim to be available next week.